December, 2023

Year

A 40 year female, presented with loose stools for more than 14 days. She was treated in a local hospital with rehydration fluids but she came to the tertiary care as she continued to have loose stools.  Stool microscopy showed the following (Images).

  1. What are the parasites seen?
  2. How should this patient be managed?
  3. What additional screening should be done?

Case answer – Posted on: 15-Dec-2023

  1. Report :
    • Stool microscopy revealed the presence of Strongyloides stercoralis rhabiditiform larvae and Cystoisospora belli oocyst
    • Strongyloides stercoralis rhabiditiform larvae are 250-300 μm long x 14-20 μm in diameter. They have characteristic short buccal cavity, and a prominent genital premordium.
    • Cystoisospora belli unsporulated oocyst is oval, 20-33 μm x 10-19 μm in size and when sporulated has two sporocysts.
  2. For Strongyloides:
    • Ivermectin 200 mg/kg daily for 2 days, if hyper-infection or disseminated infection then a prolonged course of Ivermectin for 5-7 days is recommended.
    • For Cystoisospora: Cotrimoxazole four times a day for 10 days, In HIV positive individuals, a prolonged course is administered to prevent relapses.
  3. Both the infections indicate potential immunocompromise – detailed history (corticosteroid use), additional screening of HIV, HTLV infections and follow up needed.

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